5 Simple Techniques For Allergy and Clinical Immunology
An additional DNA-primarily based approach has long been to mix allergen with bacterial DNA sequences that include CpG motifs to selectively target Toll-like receptor 9 (TLR9) expressed on human B cells and dendritic cells. The main ragweed pollen allergen Amb a 1 covalently linked to a B-style CpG-made up of oligodeoxynucleotide (ODN)131 was thriv